Hi! I quickly checked the forum, but really didn't see what I was looking for. Long story short, my senior Sheltie passed from cancer at 15.7 (I miss her so much!), and another Sheltie came into my life through divine intervention. He's about four months now. Here's my question: My last girl was never vaccinated for lepto, even though we live in a relatively wooded area. We have rabbits, mice, deer, fox, etc. Our yard is fenced in. My last vet, who has since retired, told me that standing water was an issue. Since she didn't swim or anything like that, lepto was never administered. Now, with the new baby, my new vet, who bought the practice from my last vet, is a younger man. He helped me through my senior's cancer struggle and I feel like him and I have a pretty good dialogue going on--as in, I ask questions, he answers them with explanation and no attitude. Hoorah! Anyway, he recommends doing lepto because of the wooded area I live in. He lives nearby. A dog he treated had lepto pretty recently, and by the look on his face, it was like he'd seen some serious stuff. We talked about my senior girl, and how thoughts have changed on how lepto can be transmitted now. Over a decade went by between when she was born until she passed. I realize that this vaccine only protects against certain strains, and there's no guarantee. My breeder doesn't think it'll be much of an issue should I choose to vaccinate, as he's under the impression the MDR1 gene mutation was part of the reason Shelties were having such adverse reactions. My puppy is MDR1 normal, but I sent away for a testing kit from Washington University to be 100% sure. Has anyone experienced any adverse reactions doing lepto? I'm assuming this vaccine is the four strain, but I'd have to call the office to confirm. I've been doing all of his core vaccines separately, so he's been to the vet quite a few times. I want to do what's in his best interest, but seeing how many dogs have died from vaccine reactions has scared me--and on the other hand, all of the dogs passing from lepto itself has always sent me into a cold sweat. I feel very conflicted! And my last Sheltie, who was a blue Merle and I swear had the gene mutation, was sensitive to everything and anything, so I'm worried my current boy, also a blue, will be the same. ♀️ Thoughts greatly appreciated!