I asked for advice over the years for my rescue Missy that had arthritis in her elbows. She was also very noise phobic, not just to fireworks or thunder, but sometimes a bird chirping. We know she was in pain often even with all the pain meds given daily for the last 2-3 yrs, but she started having panic attacks out of the blue a yr or so ago. She also starting pacing constantly with panting. We tried prozac and it seemed to work for a short time, but it came back. What was so hard was she would have a good day (for her) and we we were so hopeful only to have panic attacks 3 days in a row before they subsided a bit. Xanax was the only thing that seemed to help, but only at a high enough dose she slept. What was the point of having her sleep all the time? However, Monday when I knew she was leaving me at 2 pm she was fine, having a good day. She HATED car rides, but the 30 min drive to her vet she was calm and laid on the floor, but looked at me the whole drive. I wonder if I did the right thing. I am not sure. I do thank everyone here for the advice for the years.