Eevee nearly died last night after spaying!

An update on Eevee

Thank you everyone for your prayers. Eevee is back to her normal self. Eating, pooping, peeing, barking, playing and following me around the house are all back to normal. Thank goodness.

I just received a call from the vet (our regular vet is on vacation for next 10 days so his colleague called me). Apparently Eevee's AST and ALT are very high.

AST: 299 (normal range is 15-66)
ALT: 750 (normal range is 12-118)
From CBC, white cell count is little elevated: 19700 (normal range is 4-15000). But she has either UTI or vaginitis right now, so she's been on antibiotics for 3 days now.
Creatine: 0.4 (normal range is 0.5-1.6)
BUM (?): 5 (normal range is 6-31)

The vet who called me said creatine and BUM(?) level being little low is ok, but she's concerned with elevated AST and ALT. She was worried that Eevee might have a liver shunt. But she's not showing any signs of that. Actually she's not even showing signs of UTI. I just noticed that her vulva area had little bit of mucous coming out one time, and just wanted to get it checked out. They said she had bacteria, white cells, crystals etc in the urine. Our vet was sooo shocked that Eevee didn't have any accidents in the house or showing any symptoms when the urine sample looked so bad. He said to give Eevee a pat on the back. She's such a good girl... Such a sweet heart...

Anyway, this lady vet recommended that we get an ultrasound done just to make sure everything is ok. Since Eevee's back to herself, I just wanted to wait until our usual vet gets back from the vacation. I asked if anesthetics can cause liver enzymes to go up and she said yes. So I'm wondering if Eevee's liver enzymes are high because her liver was trying so hard to metabolize the anesthetics.

Since she's back to her old self, the vet I spoke to said it's not an emergency thing so we can wait until our usual vet gets back. I think I'd be more comfortable talking to him and get his opinion.

Has anyone had similar problems?? Eevee is only 13 month old and that's why the lady bet wanted to check her anatomically to see everything looks normal. She said if the ultrasound is normal, then she wants to do function tests and check for bile acids etc. Everything sounded so scary!
 
My first thought too. Ketamine and valium are the induction drugs ie the drug that actually knock her out. What premeds did she get. Ace and Butorphanol are common preansthestic drugs and are problems for MDR1 mutant/normal and mutant/mutant dogs.

There can be individual reactions to drugs but Ketamine/Val and isofluance gas are very nice drugs. Most are up in a couple hours and walking quite normally in 5-6 hours. Usually but the next morning all is back to normal.


Neutering in dogs is not a local. It is general anesthesia using the same drugs as a spay. So they should be keeping neuters too if it is the recovery from the drugs. Almost nobody keeps spays overnight here. If there is not a night staff watching them all night. NO clinic should be keeping them IMHO.

Hope your little girl is doing better now.

Well, I may have gotten the details wrong on this but when I got the boys done, Indy was a regular neuter and would have gone home the same day. But Bacca was cryptoid so they wanted to keep him overnight because it was abdominal surgery - similar to spay rather than a neuter. So they kept both boys overnight to keep company with each other.

All I was saying with with a regular neuter they generally don't stay overnight if the surgery went well without complications.
 
I just saw this. Glad to hear Eevee is back to normal and hopefully doesn't have any issues going on with her. I would definitely agree and do the MDR1 test after that reaction. I know what it feels like to see something like that happen when they're puppies. Yikes!

Oh yeah, the BUM is actually BUN. It stands for blood urea nitrogen. Don't ask me what it means though. ;) I just know BUN and creatinine are used to see how the kidney's are functioning.
 
Thank you everyone for your prayers. Eevee is back to her normal self. Eating, pooping, peeing, barking, playing and following me around the house are all back to normal. Thank goodness.

I just received a call from the vet (our regular vet is on vacation for next 10 days so his colleague called me). Apparently Eevee's AST and ALT are very high.

AST: 299 (normal range is 15-66)
ALT: 750 (normal range is 12-118)
From CBC, white cell count is little elevated: 19700 (normal range is 4-15000). But she has either UTI or vaginitis right now, so she's been on antibiotics for 3 days now.
Creatine: 0.4 (normal range is 0.5-1.6)
BUM (?): 5 (normal range is 6-31)

The vet who called me said creatine and BUM(?) level being little low is ok, but she's concerned with elevated AST and ALT. She was worried that Eevee might have a liver shunt. But she's not showing any signs of that. Actually she's not even showing signs of UTI. I just noticed that her vulva area had little bit of mucous coming out one time, and just wanted to get it checked out. They said she had bacteria, white cells, crystals etc in the urine. Our vet was sooo shocked that Eevee didn't have any accidents in the house or showing any symptoms when the urine sample looked so bad. He said to give Eevee a pat on the back. She's such a good girl... Such a sweet heart...

Anyway, this lady vet recommended that we get an ultrasound done just to make sure everything is ok. Since Eevee's back to herself, I just wanted to wait until our usual vet gets back from the vacation. I asked if anesthetics can cause liver enzymes to go up and she said yes. So I'm wondering if Eevee's liver enzymes are high because her liver was trying so hard to metabolize the anesthetics.

Since she's back to her old self, the vet I spoke to said it's not an emergency thing so we can wait until our usual vet gets back. I think I'd be more comfortable talking to him and get his opinion.

Has anyone had similar problems?? Eevee is only 13 month old and that's why the lady bet wanted to check her anatomically to see everything looks normal. She said if the ultrasound is normal, then she wants to do function tests and check for bile acids etc. Everything sounded so scary!

I believe the term is - bun - blood urea nitrogen ...nitrogen to blood in the form of urea ( bum was cuter though) :yes:
So glad she has rallied ... thank God and is getting back to herself
 
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