Heartgard Plus or Frontline Plus and Seizures????

I am so sorry to hear of Murphy's illness. It has to be terrible for you. Thank goodness I have never had to face a major illness with any of mine...not sure how I would react..would not be good, needless to say. You and Murphy are i my thoughts.
 
I hope Murphy is on the mend. A good night is a good sign. I'm sending good thoughts for Murphy's recovery.

Just an aside...I don't know what the similarities in species might be, but my 25-year-old horse has Cushings and has had it for more than five years. Her condition is completely controlled with daily medication. She's done very well on it and has no problems. So if that turns out to be Murphy's diagnosis, hopefully some medication will be the answer.
 
I fostered a little Sheltie girl that was 7 when she came into rescue. She had Cushings when she came in. She's now 11 (12 in Oct) and still going strong. I call her the Sheltie Energizer Bunny.
 
Heartgard has ivermectin, which should only be used in Collie breeds with extreme caution. Shelties are one of the breeds that carry the MDR1 gene mutation (MDR = Multi Drug Resistant gene). Over here it's called "the Collie gene". Even though heartworm meds only contain low doses, my understanding is the ivermectin can build up - and perhaps adding the Frontline on top (even tho it doesn't have ivermectin) as enough to tip him over.

Although the gene sensitivity is thought to require two copies of the gene to show, my male sheltie has only one but still has the sensitivity.

I would definitely take him off the Heargard and get him tested. I really wish these meds would carry a warning for Sheepdog/Collie breeds.

Thanks for the information. Always good to remind and re-wind. Harper Lee had a slight seizure years ago, real tiny but it was after applying Frontline. Never did it again.

My heartfelt best to Murphy. Please keep us updated on your precious baby.

Hugs,

Kate
 
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I do hope that Murphy has turned the corner and you will be able to stabilize him quickly. Seizures are scarey for the one watching and when the dog has multiple seizures in a short period of time, their muscles get sore.
I just picked up Heartguard Plus after asking if it was safe for the sheltie and the Terv. In the past I have used Revolution but the ticks are bad this year so I bought Advantix. They got the first dose of that today - I sat with them for the morning to watch for reactions - and I was planning to wait a week before adding the Heartguard. Now I am even more worried. I don't want to chance heartworm as it is becoming more prevalent around here every year and I'm hearing more and more about the dogs that didn't survive it. I guess I'll have to give the meds first thing in the morning and be prepared to shoot off to the vet.
I'll be thinking of you and Murphy and sending healing thoughts.
 
I just picked up Heartguard Plus after asking if it was safe for the sheltie and the Terv. In the past I have used Revolution but the ticks are bad this year so I bought Advantix. They got the first dose of that today - I sat with them for the morning to watch for reactions - and I was planning to wait a week before adding the Heartguard. Now I am even more worried. I don't want to chance heartworm as it is becoming more prevalent around here every year and I'm hearing more and more about the dogs that didn't survive it. I guess I'll have to give the meds first thing in the morning and be prepared to shoot off to the vet.
I'll be thinking of you and Murphy and sending healing thoughts.

I am in the same situation as you. I use k9 advantix and am going to try heartgard for the first time tomorrow night. I like to give those things right after dinner, so if something happens I'll be home. She is due for k9 advantix next weekend, so they'll be about a week a part. I am a little nervous about trying heartgard for the first time. I hate using new products when I knew the old stuff worked just fine. Grrr Interceptor!
 
I have used Heartguard or Iverhart Max with 13 shelties. No bad reaction so far since 2006. But I would caution to use it during the day & during the week for the 1st time in case of a reaction. That way the normal vet offices are open in case of a problem. My vet said there would be a reaction within 24 hrs if there was going to be one.
 
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